Gadobutrol (INN An International Nonproprietary Name is the official non-proprietary or generic name given to a pharmaceutical substance, as designated by the World Health Organization (WHO)[citation needed]. The plethora of named proprietary preparations containing a given substance can lead to confusion about the identity of the active ingredient. INNs) is a contrast agent.

References

Contrast media A medical contrast medium is a substance used to enhance the contrast of structures or fluids within the body in medical imaging. It is commonly used to enhance the visibility of blood vessels and the gastrointestinal tract (V08 ATC code V08 Contrast media is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the WHO for the classification of drugs and other medical products. Subgroup V08 is part of the anatomical group V Various)
X-ray Radiocontrast agents are a type of medical contrast medium used to improve the visibility of internal bodily structures in an X-ray based imaging techniques such as Computed tomography or Radiography (commonly known as X-ray imaging). Radiocontrast agents are typically iodine or barium compounds
Iodinated, Water-soluble
Nephrotropic, high osmolar Radiocontrast agents are a type of medical contrast medium used to improve the visibility of internal bodily structures in an X-ray based imaging techniques such as Computed tomography or Radiography (commonly known as X-ray imaging). Radiocontrast agents are typically iodine or barium compounds Diatrizoic acid Diatrizoic acid , also known as amidotrizoic acid, or 3,5-Diacetamido-2,4,6-triiodobenzoic acid, is a radiocontrast agent containing iodine# · Metrizoic acid · Iodamide Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Iotalamic acid Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Ioxitalamic acid Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Ioglicic acid Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Acetrizoic acid Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Iocarmic acid Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Methiodal · Diodone
Nephrotropic, low osmolar Radiocontrast agents are a type of medical contrast medium used to improve the visibility of internal bodily structures in an X-ray based imaging techniques such as Computed tomography or Radiography (commonly known as X-ray imaging). Radiocontrast agents are typically iodine or barium compounds Metrizamide · Iohexol Iohexol is a contrast agent, sold under the trade name Omnipaque. It is available in various concentrations, from 140 to 350 milligrams of iodine per milliliter. Omnipaque 350 is commonly used as a contrast agent during coronary angiography# · Ioxaglic acid Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Iopamidol Iopamidol is a nonionic, low-osmolar iodinated contrast agent, developed by Bracco · Iopromide · Iotrolan Iotrolan is a dimer of triiodinated isophthalic acid derivatives, used as a radiocontrast agent. It is particularly used to image spaces surrounding the central nervous system, such as the ventricles, after injection into the cerebrospinal fluid. It can also be used to image joint spaces and in endoscopic retrograde cholangiopancreatography (ERCP) · Ioversol Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Iopentol Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Iodixanol Iodixanol, is a contrast agent, sold under the trade name Visipaque. Visipaque is commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents. It is an iso-osmolar contrast agent, with an osmolality · Iomeprol Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Iobitridol Xenetix 300 of Guerbet contains Iobitridol in 300 mg iodine/ml concentration. Recommended mean doses are 1.1 to 2.8 ml/kg body mass corresponding to 0,33 to 0,84 g iodine/kg human body mass. Injected into veins it will be filtered out by the kidneys. It is used also to fill joints or the uterus · Ioxilan Ioxilan is a diagnostic contrast agent. It is injected intravenously before taking X-ray images to increase arterial contrast in the final image. It is marketed under the trade name Oxilan by Guerbet, L.L.C
Hepatotropic Iodoxamic acid Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Iotroxic acid Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Ioglycamic acid Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Adipiodone Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Iobenzamic acid Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Iopanoic acid Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Iocetamic acid Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Sodium iopodate Ipodate sodium is an iodine-containing radiopaque contrast media used for X-rays. The drug is given intravenously and the resulting contrast allows for easy resolution of the blood vasculature. The drug goes by the trade name Oragrafin · Tyropanoic acid Tyropanoic acid and its salt sodium tyropanoate are radiopaque contrast media used in cholecystography . Trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac. The molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in bones to produce a visible image. After injection it is rapidly excreted · Calcium iopodate
Iodinated, Non-water-soluble Ethyl esters Ethyl acetate is the organic compound with the formula CH3COOCH2CH3. This colorless liquid has a characteristic sweet smell (similar to pear drops) like certain glues or nail polish removers, in which it is used. Ethyl acetate is the ester from ethanol and acetic acid; it is manufactured on a large scale for use as a solvent. In 1985, about 400k of iodised fatty acids In chemistry, especially biochemistry, a fatty acid is a carboxylic acid with a long unbranched aliphatic tail , which is either saturated or unsaturated. Carboxylic acids as short as butyric acid (4 carbon atoms) are considered to be fatty acids, whereas fatty acids derived from natural fats and oils may be assumed to have at least eight carbon · Iopydol Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Propyliodone Propyliodone is a molecule used as a contrast medium · Iofendylate Nephrotropic, low osmolar: Metrizamide · Iohexol # · Ioxaglic acid · Iopamidol · Iopromide · Iotrolan · Ioversol · Iopentol · Iodixanol · Iomeprol · Iobitridol · Ioxilan · Lipiodol
Non-iodinated Barium sulfate Barium sulfate is a white crystalline solid with the chemical formula BaSO4. It is insoluble in water and other traditional solvents but is soluble in concentrated sulfuric acid. The mineral barite is composed largely of barium sulfate and is a common ore of barium. It is often extracted in a blast furnace, as it can cope with high temperature#
MRI MRI contrast agents are a group of contrast media used to improve the visibility of internal body structures in Magnetic resonance imaging . The most commonly used compounds for contrast enhancement are gadolinium-based. MRI contrast agents alter the relaxation times of tissues and body cavities where they are present, which depending on the image
Paramagnetic Paramagnetism is a form of magnetism which occurs only in the presence of an externally applied magnetic field. Paramagnetic materials are attracted to magnetic fields, hence have a relative magnetic permeability of ≥1 . The magnetic moment induced by the applied field is linear in the field strength and rather weak. It typically requires a Gadopentetic acid Gadopentetic acid is the first paramagnetic magnetic resonance imaging (MRI) contrast agent. First described in 1981, and introduced in 1988, it is used to assist imaging of blood vessels and of inflamed or diseased tissue where the blood vessels become 'leaky'. It is often used when viewing intracranial lesions with abnormal vascularity or · Gadoteric acid Gadoteric acid is a gadolinium macrocycle used as a contrast medium · Gadodiamide Gadodiamide is a gadolinium based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. It is commonly marketed under the trade name Omniscan · Gadolinium Gadolinium is a chemical element that has the symbol Gd and atomic number 64. It is a silvery-white, malleable and ductile rare-earth metal. Gadolinium has exceptionally high absorption of neutrons and therefore is used for shielding in neutron radiography and in nuclear reactors. Because of its paramagnetic properties, solutions of organic · Gadoteridol Gadoteridol is a magnetic resonance contrast agent, used particularly in the imaging of the central nervous system. It is sold under the brand name ProHance · Mangafodipir · Gadoversetamide Gadoversetamide is a gadolinium compound used as a contrast agent in magnetic resonance imaging , particularly imaging of the brain, spine and liver. It is marketed under the trade name OptiMARK · Ferric ammonium citrate Ammonium ferric citrate is a food additive with E number E381 used as an acidity regulator.[citation needed] It is a green or reddish-brown powder which is very soluble in water · Gadobenic acid · Gadobutrol · Gadoxetic acid
Superparamagnetic Ferumoxsil · Ferristene · Iron oxide, nanoparticles
Other Perflubron
Ultrasound Microspheres of human albumin · Microparticles of galactose · Perflenapent · Microspheres of phospholipids · Sulfur hexafluoride
#WHO-EM. ‡Withdrawn from market. CLINICAL TRIALS: †Phase III. §Never to phase III
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